Continuous Perfusion Monoclonal Antibody Model

Underwrite 500-liter continuous perfusion single-use bioreactors with alternating tangential flow (ATF) cell retention filters (operating for 60 consecutive days at 100 million cells/mL density with 10x higher volumetric protein titer than batch fed-batch reactors). Model pharma CDMO biomanufacturing fees ($280/gram mAb), and 15-yr IRR.