Continuous Enzymatic mRNA Vaccine Synthesis Model

Underwrite continuous microfluidic in-vitro transcription (IVT) lines performing continuous Vaccinia enzymatic 5-prime capping and Cap-1 methylation with inline HPLC purification (producing 100 million mRNA vaccine doses per week in a compact benchtop cleanroom footprint). Model vaccine CDMO manufacturing contracts ($4.50/dose), and 15-yr IRR.